Visionar Preclinical AB is a professional CRO for outsourcing preclinical studies. Our aim is to provide customers with a fast and reliable route to clinical phase I-II studies.

We offer a wide range of toxicity studies, pharmacokinetic studies, effect studies and other analyses essential in the preclinical phase. We have an extensive experience of designing large and specialized in vivo studies where untraditional ways to tackle problems are essential.

We work flexibly and adapt to the project needs. Thereby, we take care of the creativity needed to identify new, robust, models for the preclinical phase. Our experience from small and large projects within many different disease therapies makes possible a fast and effective delivery of data to our customers.

Our services include:

• Development of preclinical strategies
  
• Pilot in vivo studies
  
• “Proof-of-concept” studies
  
• Tests of toxicity after acute and repeated administration
  
• Pharmacokinetic studies
  
• Haematology
  
• Clinical chemistry
  
• Histopathology
  
• Immunisations
  
• Bioanalysis, genotoxicity, and safety pharmacology in collaboration with our test sites
  

Specialities

• Ophtalmology
  
• Ocular pharmacokinetics, bioavailability
  
• Tonometry, pachymetry
  
• Acute, sub-chronic, and chronic ocular toxicity
  
• DNA vaccines, including electroporation
  
• Toxicity after acute and repeated intradermal or intramuscular administration
  
• Medical devices
  
• Biocompatibility after subcutaneous implantation
  
• Acute toxicity of extracts

Disease models

• DSS- induced colitis (more information)
  
• Evaluation of cytostatic potential with use of hollow-fibres and xenograft (more information)
• The MCAO stroke experimental model (more information)
  

Additional services

• Expert reports
  
• “Second opinion” evaluations
  
• Customer designed studies
  
• Investigators brochure (IB) in collaboration with Stricent
  

Visionar Preclinical AB is part of the Swedish Medical Products Agency GLP inspection program. All studies are performed in compliance according to OECDs GLP guidelines. Complete quality assurance is performed on studies performed for regulatory purposes.

Animal care and husbandry is according to EU guidelines. All studies have been granted by Uppsala Animal Ethics Committee.